Rostrum® Plus

Ear emulsion.

Otic, antibacterial and antifungal emulsion.

Each mL of emulsion contains:
Enrofloxacin……………………. 5 mg
Silver Sulfadiazine………… 10 mg
Excipients c.s.p……………….. 1 mL

Indicated in the treatment of acute or chronic otitis externa in dogs, caused by bacteria and fungi sensitive to Enrofloxacin and/or Silver Sulfadiazine.

5 to 10 drops in dogs weighing 15 kilos or less, and 10 to 15 drops in dogs weighing more than 15 kilos. Administer 2 times a day for 14 days.
Topical administration.

Clean the ear canal, then administer Rostrum® Plus in sufficient quantity to cover the external ear canal, gently massage the ear to ensure a complete and even distribution of the medication throughout the canal.

Dogs.

• Do not use in dogs that are hypersensitive to quinolones and/or sulfonamides.
• Do not use in dogs with perforation of the tympanic membrane.
• Do not use during pregnancy and breastfeeding.

• Keep out of reach of children and pets.
• The use of this association has not been evaluated in dogs with perforation of the tympanic membrane. Consequently, before administering the product, the external ear canal should be examined to ensure that there is no rupture of the tympanic membrane, in order to avoid contamination of the middle ear, as well as vestibular and cochlear lesions. If there are signs of deafness or vestibular abnormalities during administration of the product, discontinue use.
• Quinolones should be used with caution in animals with central nervous system (CNS) disorders. In these animals, in rare cases, quinolones have been associated with CNS stimulation, which can cause convulsions.
• Fluoroquinolones, such as Enrofloxacin, should not be used as a first line of treatment, unless no therapeutic alternative is available. When used as a second treatment, it should be on the basis of susceptibility studies.

• With the exception of possible cartilage abnormalities in young animals, the adverse effect profile of Enrofloxacin is generally limited to gastrointestinal problems (vomiting, anorexia), although rare incidents of elevated liver enzymes, ataxia, seizures, depression, and lethargy have also been reported.
• No evidence of systemic toxicity by Silver Sulfadiazine has been reported in dogs, and even 1% Silver Sulfadiazine ear suspensions have been used in dogs for more than three months without incident.

It is not recommended for use concomitantly with other pharmaceutical products.

Wash your hands after administering the product.

Keep in a cool place, at a temperature between 15 and 30°C, away from light.

Dispose of unused product residues in their original, tightly closed containers. Dispose of waste of this product with caution along with household waste.

• For Chile: Sale under prescription Retained Veterinary Doctor.
• For Export: Sale under prescription Veterinary Doctor.

VETERINARY USE
SHAKE BEFORE USE

Chile: Reg. SAG N° 1523
Bolivia: Reg. SENASAG PUV-F-N° 006147/14
El Salvador: VE2014084963
Peru: Reg. SENASA F.82.73.I.0022

Container with 15 mL

Laboratorio Drag Pharma Chile Invetec S.A.
Lautaro N° 300. Quilicura. Santiago. Chile.