Micospectone®

Solution for injection.

Antimicrobials.

Each 100 mL contains:
lincomycin hydrochloride……………………… 5.67 g (equivalent to 5.0 g lincomycin)
spectinomycin hydrochloride…………….. 15.0 g (spectinomycin equivalent 10.0 g)
Excipients c.s.p. …………………………………. 100 ml.

Mycospectone® is indicated for infections caused by the following bacterial species: Staphylococcus spp., Streptococcus spp., Diplococcus spp., Corynebacterium spp., Bacillus spp., Clostridium spp., coliform bacilli, Klebsiella spp., Salmonella spp., Haemophilus spp., Pasteurella spp., Leptospira spp., Bordetella spp., Campylobacter spp., Fusobacterium spp., Mycoplasma spp.
Cattle, sheep, goats: respiratory diseases and enteritis, foot infections, mastitis, clostridiosis, mycoplasmosis.
Pigs: bacterial and mycoplasma pneumonia, septic arthritis, bacterial enteritis, Haemophilus pulmonitis.

Micospectone is a 1:2 combination of lincomycin and spectinomycin. Lincomycin, an antibiotic that belongs to the lincosamine family, has a broad spectrum of action, mainly against Gram-positive bacteria and mycoplasmas.
On the other hand, it has the pharmacokinetic characteristic of enormous diffusibility to all organs and tissues where, whatever the route of administration, it reaches concentrations higher than blood concentrations.
On the other hand, spectinomycin, an aminocyclitholic antibiotic, has a slightly larger spectrum of action compared to lincomycin, since it acts on some Gram-positives, most Gram-negatives and mycoplasmas. Administered parenterally, spectinomycin is sufficiently diffused throughout the body.
The contemporaneous use of the two active ingredients allows to obtain an extensive synergism of action against numerous bacterial agents, including mycoplasmas, reaching a minimum inhibitory concentration, significantly reduced compared to that manifested with antibiotics used separately.
This synergism is generally developed by injection, while orally, as spectinomycin is practically not absorbed by the gastroenteric system, the phenomenon occurs only in localized infections in the sector against diseases of birds, piglets and unweaned calves.

Cattle, pigs, sheep and goats.

Administer by deep intramuscular.

Dosage of the active substance

• Cattle, sheep, goats:
  5 mg of lincomycin and 10 mg of spectinomycin per kg body weight every 24 hours and in severe cases every 12 hours for 4 or 2 days, respectively.
• Pigs:
  5 mg of lincomycin and 10 mg of spectinomycin per kg body weight every 24 hours and in severe cases every 12 hours for 3-7 days.

Product Dosage

• Cattle, sheep, goats: 1 ml per 10 kg body weight every 24 hours and in severe cases every 12 hours for 4 or 2 days, respectively.
• Pigs: 1 ml per 10 kg body weight every 24 hours and in severe cases every 12 hours for 3-7 days.

• Do not administer during gestation, lactation or in breeding animals.
• Do not administer to animals hypersensitive to lincomycin or spectinomycin.
• Do not administer the product to horses and rabbits.
• Do not administer the product together with muscle relaxants, macrolides or other aminoglycosides.

• The use of the product in animal species not indicated on the label may cause side effects at the gastroenteric level.
• In cattle, if the volume to be injected is greater than 50 ml, it is recommended to divide the dose into 2 or more inoculation points.
• In pigs, a similar procedure is recommended when the volume to be injected is greater than 20 mL
• Keep out of reach of children.

• Sheep and Goats:
  Meat: 20 days.
  Milk: Do not administer to animals producing milk for human consumption.
• Cattle:
  Meat: 20 days.
  Milk: 72 hours.
• Pigs:
  Meat: 13 days.

• Occasional phenomena of transient diarrhoea have been reported in sheep, goats and pigs after administration of the product.
• Decreased appetite and milk production have been observed in goats.

• Handle with care if you are allergic to lincomycin or spectinomycin.
• In case of contact with skin, eyes or mucous membranes, wash immediately with plenty of water, if there is irritation immediately go to a medical center and show the product label.
• In case of accidental injection, go immediately to a medical center and show the product label.

Empty containers can be discarded as household waste, without any special precautions. Do not dispose of containers with product residues on the ground or in waterways.
Contact the importing company or companies specialized in waste disposal, to receive recommendations on the disposal of expired or unused products.

VETERINARY USE

Store at a temperature between 2 and 30°C.
Once opened, use within 28 days. Discard the unused product after that period of time.

Sale by prescription to the Veterinary Doctor.

Bottle with 100 mL

FATRO S.p.A.
Via Emilia, 285 – 40064 Ozzano Emilia (Bologna) Italy.

Laboratorio Drag Pharma Chile Invetec S.A.
Lautaro N° 300 • Quilicura • Santiago • Chile