{"id":9784,"date":"2021-04-05T00:00:00","date_gmt":"2021-04-05T03:00:00","guid":{"rendered":"https:\/\/dragpharma.cl\/producto\/dalmarelin\/"},"modified":"2024-05-28T11:56:20","modified_gmt":"2024-05-28T14:56:20","slug":"dalmarelin","status":"publish","type":"product","link":"https:\/\/dragpharma.cl\/en\/producto\/dalmarelin\/","title":{"rendered":"Dalmarelin\u00ae"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"

DALMARELIN is an injectable aqueous solution containing lecirelin, a synthetic analogue of the hypothalamic polypeptide hormone GnRH, which induces the release of the gonadotropin hormones LH and FSH from the frontal pituitary….<\/p>\n

Read more<\/a><\/i><\/span><\/span><\/p>\n","protected":false},"featured_media":7761,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[2362],"product_tag":[],"especies":[1740,1741],"therapeutic_action":[1756],"class_list":{"0":"post-9784","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","7":"especies-bovines","8":"especies-horses","9":"therapeutic_action-others","11":"first","12":"instock","13":"product-type-simple"},"acf":{"id_favoritos":"1241","segundo_titulo":"","efecto_medico":"Synthetic analog of GnRH","archivos_n":null,"ficha_tecnica":[{"titulo":"Pharmaceutical form","tipo_de_contenido":"contenido","contenido":"Injectable solution.","tabla":null},{"titulo":"Therapeutic Action","tipo_de_contenido":"contenido","contenido":"Synthetic analog of GnRH.","tabla":null},{"titulo":"Species","tipo_de_contenido":"contenido","contenido":"Cows and mares.","tabla":null},{"titulo":"Composition","tipo_de_contenido":"contenido","contenido":"Each mL of solution for injection contains:\r\nActive principle:\r\nLecirelin Acetate .......................................26.5 \u03bcg\r\n(equivalent to 25 \u03bcg of Lecirelin)\r\nExcipients csp ..............................................1 mL","tabla":null},{"titulo":"Properties","tipo_de_contenido":"contenido","contenido":"DALMARELIN is an injectable aqueous solution containing lecirelin, a synthetic analogue of the hypothalamic polypeptide hormone GnRH, which induces the release of the gonadotropin hormones LH and FSH from the frontal pituitary.\r\nLecirelin differs from natural hormones in that it is a nonapeptide and not a decapeptide by substitution of glycine in the tenth position with a highly lipophilic ethyl amine. This change in structure increases the affinity for specific pituitary receptors, resulting in an increase in LH and FSH levels, as well as a prolongation of their effects for a period greater than 240 minutes, unlike the 90 minutes of the natural hormone.\r\nDALMARELIN is indicated in cases of low fertility due to immaturity or delayed maturity of the follicle and ovulation due to insufficient secretion of FSH and LH by the pituitary gland. The inoculation of gonadotropins determines exogenous effects that are not physiologically controllable. On the other hand, the administration of DALMARELIN determines the secretion of pituitary gonadotropins that is controllable by the body through negative feedback mechanisms.","tabla":null},{"titulo":"Indications","tipo_de_contenido":"contenido","contenido":"Cows:<\/strong>\r\n