{"id":9729,"date":"2020-07-23T00:00:00","date_gmt":"2020-07-23T03:00:00","guid":{"rendered":"https:\/\/dragpharma.cl\/producto\/dermisolona-2\/"},"modified":"2024-05-28T12:48:48","modified_gmt":"2024-05-28T15:48:48","slug":"dermisolone-oral-suspension","status":"publish","type":"product","link":"https:\/\/dragpharma.cl\/en\/producto\/dermisolone-oral-suspension\/","title":{"rendered":"Dermisolona\u00ae Oral suspension"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"<p>It is indicated as an aid in the treatment of inflammatory and allergic disorders in dogs and cats. In dogs it is also indicated as an immunosuppressant in autoimmune diseases, as therapy for chronic inflammatory bowel disease and in the treatment of hypoadrenocorticism&#8230;.<\/p>\n<p><span class=\"button-ver-mas\"><a class=\"understrap-read-more-link\" href=\"https:\/\/dragpharma.cl\/en\/producto\/dermisolone-oral-suspension\/\">Read more<\/a><span class=\"arrow\"><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/span><\/span><\/p>\n","protected":false},"featured_media":7740,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[1749,1747],"product_tag":[2201,2250,2208,2248,2249,2247,2251],"especies":[1739,1737],"therapeutic_action":[1750,1782],"class_list":{"0":"post-9729","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cat-antiinflammatories-analgesic","7":"product_cat-cat-dermatological","8":"product_tag-allergy-en","9":"product_tag-alone","10":"product_tag-corticosteroid-en","11":"product_tag-dermi-en","12":"product_tag-dermi-solona-en","13":"product_tag-dermisolone","14":"product_tag-solona-en","15":"especies-dogs","16":"especies-cats","17":"therapeutic_action-antiinflammatories-analgesic","18":"therapeutic_action-dermatological","20":"first","21":"instock","22":"product-type-simple"},"acf":{"id_favoritos":"1215","segundo_titulo":"Anti-inflammatories\/Analgesics","efecto_medico":"Steroid anti-inflammatory - Antiallergic","archivos_n":null,"ficha_tecnica":[{"titulo":"Pharmaceutical form","tipo_de_contenido":"contenido","contenido":"Oral suspension.","tabla":null},{"titulo":"Therapeutic action","tipo_de_contenido":"contenido","contenido":"Steroid anti-inflammatory - Antiallergic.","tabla":null},{"titulo":"Target species","tipo_de_contenido":"contenido","contenido":"Dogs and cats.","tabla":null},{"titulo":"Composition","tipo_de_contenido":"contenido","contenido":"Each mL of oral suspension contains:\r\nPrednisolone Acetate................................4.5 mg\r\n(Equivalent to 4 mg of Prednisolone base)\r\nExcipients q.s.................................................1 mL","tabla":null},{"titulo":"Indications of use","tipo_de_contenido":"contenido","contenido":"It is indicated as an aid in the treatment of inflammatory and allergic disorders in dogs and cats. In dogs it is also indicated as an immunosuppressant in autoimmune diseases, as therapy for chronic inflammatory bowel disease and in the treatment of hypoadrenocorticism.","tabla":null},{"titulo":"Route of administration","tipo_de_contenido":"contenido","contenido":"Oral administration.","tabla":null},{"titulo":"How to use","tipo_de_contenido":"contenido","contenido":"Shake the suspension before use, then extract the dose of product with the measuring syringe or dropper and administer directly into the oral cavity.","tabla":null},{"titulo":"Dosage, frequency of use and duration of treatment:","tipo_de_contenido":"tabla","contenido":"","tabla":{"acftf":{"v":"1.3.21"},"p":{"o":{"uh":0},"ca":""},"c":[{"p":""},{"p":""},{"p":""},{"p":""}],"h":[{"c":""},{"c":""},{"c":""},{"c":""}],"b":[[{"c":""},{"c":""},{"c":"DOSAGE OF THE ACTIVE INGREDIENT"},{"c":"PRODUCT DOSAGE.\n(1 mL = 26 drops of product)"}],[{"c":"ANTI-INFLAMMATORY AND ANTI-ALLERGIC THERAPY"},{"c":"DOGS"},{"c":"0.5 to 1 mg\/kg of weight, every 12 to 24 hours, for 3 to 5 days."},{"c":"1.5 to 2.5 mL per 10 kg of weight, or 4 to 7 drops per kg of weight, every 12 to 24 hours, for 3 to 5 days."}],[{"c":""},{"c":"CATS"},{"c":"1 to 2 mg\/kg of weight, every 12 to 24 hours, for 3 to 5 days."},{"c":"1.5 to 2.5 mL per 5 kg of weight or 7 to 13 drops per kg of weight, every 12 to 24 hours, for 3 to 5 days."}],[{"c":""},{"c":""},{"c":"In prolonged treatments, it is recommended to reduce the effective dose to the lowest effective dose and administer it every other day in the morning for dogs, and in the afternoon for cats (to respect the circadian rhythm)."},{"c":"In prolonged treatments, it is recommended to reduce the effective dose to the lowest effective dose and administer it every other day in the morning for dogs, and in the afternoon for cats (to respect the circadian rhythm)."}],[{"c":""},{"c":""},{"c":""},{"c":""}],[{"c":"IMMUNOSUPPRESSANT"},{"c":"DOGS"},{"c":"1 to 4 mg\/Kg\/ every 24 hours for 2 to 14 days. Then, 0.5 to 2 mg\/Kg\/ every 24 hours, for 14 days.\nThen reduce the dose at regular intervals (2 to 6 weeks), until reaching the maintenance dose of 0.5 to 1 mg\/Kg\/alternate days. (*)"},{"c":"2.5 to 10 mL per 10 kg of weight per day, or 7 to 26 drops per kg of weight every 24 hours, for 2 to 14 days. Then, 1.3 to 5 mL per 10 kg of weight per day, or 4 to 13 drops per kg of weight every 24 hours, for 2 to 14 days. Then reduce the dose at regular intervals (2 to 6 weeks), until reaching the maintenance dose of 1.5 to 2.5 mL per 10 kg of weight, or 4 to 7 drops per kg of weight, on alternate days. . (*)(**)"}],[{"c":""},{"c":""},{"c":""},{"c":""}],[{"c":"CHRONIC INFLAMMATORY BOWEL DISEASE"},{"c":"DOGS"},{"c":"1 to 4 mg\/kg body weight every 12 to 24 hours for 2 to 4 weeks, then slowly reduce the dose at intervals of 10 days to 2 weeks depending on clinical response, until reaching a maintenance dose of 0.5 to 1 mg\/Kg every other day (*)"},{"c":"2.5 to 10 mL per 10 kg of weight per day, or 7 to 26 drops per kg of weight, every 12 to 24 hours, for 2 to 4 weeks, then slowly reduce the dose at intervals of 10 to 2 days. weeks depending on the clinical response, until reaching the maintenance dose of 1.5 to 2.5 mL per 10 kg of weight, or 4 to 7 drops per kg of weight, on alternate days. (*)(**)"}],[{"c":""},{"c":""},{"c":""},{"c":""}],[{"c":"HYPOADRENOCORTICISM"},{"c":"DOGS"},{"c":"0.2 to 0.4 mg\/kg of weight, every 24 hours, permanently."},{"c":"0.5 to 1 mL per 10 kg of weight or 2 to 3 drops per kg of weight every 24 hours, permanently."}]]}},{"titulo":"*","tipo_de_contenido":"tabla","contenido":"","tabla":{"acftf":{"v":"1.3.21"},"p":{"o":{"uh":0},"ca":""},"c":[{"p":""}],"h":[{"c":""}],"b":[[{"c":"(*) The duration of therapy varies depending on the intensity of the condition and the remission of symptoms, and may last for several weeks or months. In these cases, it is recommended to use the minimum effective dose, on an alternate day basis.\n(**) 1 mL of Dermisolone\u00ae Oral Suspension is equivalent to 26 drops of product."}]]}},{"titulo":"Adverse effects and adverse reactions","tipo_de_contenido":"contenido","contenido":"<ul>\r\n \t <li>Administered short-term, Prednisolone is unlikely to cause harmful effects, even in massive doses. Adverse effects are generally associated with chronic therapies, especially at high doses or if an alternate-day regimen is not followed.<\/li>\r\n \t <li>The most common adverse effects are polyuria, polydipsia and polyphagia; and are preferably associated with anti-inflammatory doses.<\/li>\r\n \t <li>Regarding immunosuppressive doses and extensive treatments, adverse reactions are more likely to occur and potentially more pronounced. These effects, observable on rare occasions, manifest as symptoms of hyperadrenocorticism (Cushing's Syndrome): dull and dry coat, weight gain, panting, vomiting, diarrhea, hepatomegaly with the consequent alteration of the concentration of liver enzymes in the serum, pancreatitis, gastrointestinal ulceration (particularly when used with NSAIDs), lipidemia, alteration of insulin requirements, activation or intensification of Diabetes Mellitus, muscle wasting and behavioral changes (depression, lethargy, vices).<\/li>\r\n \t <li>In prolonged treatments, an increase in the incidence of osteoporosis is described, especially in older dogs.<\/li>\r\n<\/ul>","tabla":null},{"titulo":"Special precautions for use","tipo_de_contenido":"contenido","contenido":"<ul>\r\n \t <li>In case of prolonged treatments with Prednisolone, a greater protein intake should be provided to keep the animal in a positive nitrogen balance.<\/li>\r\n \t <li>A delaying effect on wound healing has not been described, however, such a possibility should be considered when used in surgery.<\/li>\r\n \t <li>Prolonged therapy with glucocorticoids can suppress adrenocortical activity, so its suspension should be carried out gradually to ensure the gradual return of ACTH and endogenous corticosteroid functions.<\/li>\r\n \t <li>Administer with caution to animals that have diabetes, osteoporosis or are recovering from a bone fracture, predisposition to thrombophlebitis, hypertension, congestive heart failure, renal failure or active tuberculosis.<\/li>\r\n \t <li>The anti-inflammatory effects can mask signs of infection.<\/li>\r\n \t <li>Administer with caution to growing animals as it may cause retardation.<\/li>\r\n \t <li>Administer with caution to animals with liver failure.<\/li>\r\n<\/ul>","tabla":null},{"titulo":"Contraindications","tipo_de_contenido":"contenido","contenido":"<ul>\r\n \t <li>Do not use in animals with Cushing's syndrome.<\/li>\r\n \t <li>Do not use in patients with systemic fungal infections or viral infections.<\/li>\r\n \t <li>Do not use in animals with peptic or corneal ulcer.<\/li>\r\n \t <li>Do not administer to pregnant females.<\/li>\r\n \t <li>Do not use in animals hypersensitive to any of the components of this product.<\/li>\r\n \t <li>Do not administer together with vaccines.<\/li>\r\n<\/ul>","tabla":null},{"titulo":"Warnings","tipo_de_contenido":"contenido","contenido":"Keep out of the reach of children.","tabla":null},{"titulo":"Use during pregnancy, lactation and in reproductive animals","tipo_de_contenido":"contenido","contenido":"Do not administer to pregnant or lactating females.","tabla":null},{"titulo":"Interaction with other pharmaceutical products","tipo_de_contenido":"contenido","contenido":"It is recommended to avoid the concomitant administration of Prednisolone with:\r\n<ul>\r\n \t <li>Amphotericin B or kaliuretic diuretics (furosemide, thiazides), as hypokalemia may occur. Digitalis may increase the possibility of toxicity if hypokalemia occurs.<\/li>\r\n \t <li>Phenytoin, phenobarbital and Rifampin, because they can increase the metabolism of corticosteroids.<\/li>\r\n \t <li>Ciclosporine, because blood levels of both drugs can be increased with mutual inhibition of hepatic metabolism.<\/li>\r\n \t <li>With ulcerogenic drugs (for example, non-steroidal anti-inflammatory drugs) as the risk of gastrointestinal ulceration may increase.<\/li>\r\n \t <li>Cyclophosphamide, since corticosteroids can inhibit the hepatic metabolism of the chemotherapy drug.<\/li>\r\n \t <li>Patients treated with corticosteroids at immunosuppressive doses should generally not receive live attenuated virus vaccines, because viral replication may be enhanced.<\/li>\r\n \t <li>Insulin requirements may be increased in patients receiving glucocorticoids.<\/li>\r\n<\/ul>","tabla":null},{"titulo":"Overdose","tipo_de_contenido":"contenido","contenido":"Given short-term, glucocorticoids are unlikely to cause harmful effects, even in massive doses. Adverse effects are generally associated with chronic therapies, especially at high doses or if an alternate-day regimen is not followed.","tabla":null},{"titulo":"Special precautions for the operator","tipo_de_contenido":"contenido","contenido":"<ul>\r\n \t <li>In case of contact with skin, eyes or mucous membranes, wash immediately with plenty of water.<\/li>\r\n \t <li>In case of irritation, go to a medical center and show the product insert.<\/li>\r\n \t <li>In case of accidental ingestion, go immediately to a medical center and show the product insert.<\/li>\r\n \t <li>Do not handle by pregnant women.<\/li>\r\n<\/ul>","tabla":null},{"titulo":"Storage conditions","tipo_de_contenido":"contenido","contenido":"Store in a cool, dry place, at a temperature between 2 and 30\u00ba C.\r\nOnce the bottle is opened, use within 30 days.","tabla":null},{"titulo":"Special precautions for disposal of unused product or waste material","tipo_de_contenido":"contenido","contenido":"Empty containers can be discarded as household waste, without any special precautions. Do not dispose of containers with product remains on the ground or in water courses. For expired or unused products, contact the manufacturing laboratory.","tabla":null},{"titulo":"Observations","tipo_de_contenido":"contenido","contenido":"<strong>VETERINARY USE\r\n<\/strong><strong>SHAKE BEFORE USE<\/strong>","tabla":null},{"titulo":"Terms of sale","tipo_de_contenido":"contenido","contenido":"Sale under Veterinary Medical prescription.","tabla":null},{"titulo":"Registry","tipo_de_contenido":"contenido","contenido":"Reg. SAG N\u00b0 2281","tabla":null},{"titulo":"Presentation","tipo_de_contenido":"contenido","contenido":"Container with 30 mL","tabla":null},{"titulo":"Prepared and distributed by","tipo_de_contenido":"contenido","contenido":"<strong><a title=\"Laboratorio Drag Pharma Chile Invetec S.A\" href=\"https:\/\/dragpharma.cl\/\" target=\"_blank\" rel=\"noopener\">Laboratorio Drag Pharma Chile Invetec S.A<\/a>.\r\n<\/strong>Lautaro N\u00b0 300. Quilicura. Santiago. Chile.","tabla":null}],"is_featured_product":"","related_prod":[8827,8652,9699]},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dermisolona\u00ae Oral suspension - Drag Pharma<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dragpharma.cl\/producto\/dermisolona-suspension-oral\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dermisolona\u00ae Oral suspension - Drag Pharma\" \/>\n<meta property=\"og:description\" content=\"It is indicated as an aid in the treatment of inflammatory and allergic disorders in dogs and cats. 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