{"id":9279,"date":"2024-04-19T00:00:00","date_gmt":"2024-04-19T03:00:00","guid":{"rendered":"https:\/\/dragpharma.cl\/producto\/ovolute\/"},"modified":"2024-10-23T13:36:49","modified_gmt":"2024-10-23T16:36:49","slug":"ovolute","status":"publish","type":"product","link":"https:\/\/dragpharma.cl\/en\/producto\/ovolute\/","title":{"rendered":"Ovolute\u00ae"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"<p><strong>Ovolute\u00ae<\/strong> is a synthetic prostaglandin used for:<strong><br \/>\n<\/strong><\/p>\n<ul>\n<li>Induction or synchronization of estrus.<\/li>\n<li>Physiological or pathological expulsion of uterine contents.<\/li>\n<\/ul>\n<p>&#8230;<\/p>\n<p><span class=\"button-ver-mas\"><a class=\"understrap-read-more-link\" href=\"https:\/\/dragpharma.cl\/en\/producto\/ovolute\/\">Read more<\/a><span class=\"arrow\"><i class=\"fa fa-angle-right\" aria-hidden=\"true\"><\/i><\/span><\/span><\/p>\n","protected":false},"featured_media":19885,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[1780],"product_tag":[2055,2051,2053],"especies":[1740,1741,1742,1743],"therapeutic_action":[1781],"class_list":{"0":"post-9279","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cat-reproductive","7":"product_tag-ovolute-en","8":"product_tag-prostaglandin-en","9":"product_tag-synchronization","10":"especies-bovines","11":"especies-horses","12":"especies-ovines-and-caprines","13":"especies-porcines","14":"therapeutic_action-reproductive","16":"first","17":"instock","18":"product-type-simple"},"acf":{"id_favoritos":"1012","segundo_titulo":"Reproductive","efecto_medico":"Synthetic Prostaglandin","archivos_n":null,"ficha_tecnica":[{"titulo":"Dosage form","tipo_de_contenido":"contenido","contenido":"Solution for injection.","tabla":null},{"titulo":"Therapeutic action","tipo_de_contenido":"contenido","contenido":"Synthetic prostaglandin.","tabla":null},{"titulo":"Composition","tipo_de_contenido":"contenido","contenido":"Each 100 mL of solution for injection contains:\nCloprostenol Sodium....................................... 7.89 mg\n(Equivalent to 7.5 mg of D(+)-Cloprostenol base)\nExcipients c.s.p................................................ 100 mL","tabla":null},{"titulo":"Pharmacological effects","tipo_de_contenido":"contenido","contenido":"D-Cloprostenol is a synthetic analogue of PGF2 and has a biological activity similar to this natural endogenous prostaglandin. D-Cloprostenol is capable of producing in small doses the luteolytic and myometrial-stimulating effects of PGF2, which is the basis for its therapeutic indications.","tabla":null},{"titulo":"Target Species","tipo_de_contenido":"contenido","contenido":"Cattle, sheep, horses and pigs.","tabla":null},{"titulo":"Indications for use","tipo_de_contenido":"contenido","contenido":"<ul>\n \t<li><strong>Induction or synchronization of estrus.\n<\/strong>If a functional corpus luteum is diagnosed, <strong style=\"font-size: 1rem;\">Ovolute\u00ae<\/strong> injection <span style=\"font-size: 1rem;\"> causes luteolysis and estrus with ovulation between the 2nd and 4th day after administration.\n<\/span>The corpus luteum or cysts disappear within a few days. <strong style=\"font-size: 1rem;\">Ovolute\u00ae<\/strong><span style=\"font-size: 1rem;\"><span style=\"font-size: 1rem;\"> can also be used to shorten the cycle or synchronization of estrus.<\/span><\/span><\/li>\n \t<li><strong>Physiological or pathological expulsion of uterine contents.\n<\/strong>Due to the stimulating effect of <strong style=\"font-size: 1rem;\">Ovolute\u00ae<\/strong><span style=\"font-size: 1rem;\">  Onto the muscles of the uterus, the contents of the uterus are expelled. This effect can be used for induction of labor (no earlier than 260 days in cattle and 112 days in pigs), abortion (before day 150 in cattle and 35 days in horses) and endometritis. Abortion or expulsion usually occurs on the 1st or 2nd day after injection.<\/span><\/li>\n<\/ul>","tabla":null},{"titulo":"Route of administration","tipo_de_contenido":"contenido","contenido":"Intramuscular.","tabla":null},{"titulo":"Dose","tipo_de_contenido":"contenido","contenido":"<ul>\n \t<li><strong>Cattle:<\/strong> 2 mL (equivalent to 150 ug of D-Cloprostenol), in all indications.\n- Estrus induction and ovulation: From the 2nd day after administration, animals should receive adequate estrus monitoring.\n- Estrus synchronization:<span style=\"font-size: 1rem;\"><span style=\"font-size: 1rem;\"><span style=\"font-size: 1rem;\">  Repeat the dose 11 days later. Estrus occurs 2 to 4 days later.<\/span><\/span><\/span><\/li>\n \t<li><strong>Horses:<\/strong> 0.3 to 1 mL (equivalent to 25 to 75 ug of D-Cloprostenol), in all indications.\n- Estrus induction and cycle shortening.\n- In labor induction:<span style=\"font-size: 1rem;\"><span style=\"font-size: 1rem;\"><span style=\"font-size: 1rem;\">  Administer after day 320 of gestation. Delivery usually takes place within a few hours.<\/span><\/span><\/span><\/li>\n \t<li><strong>Pigs:<\/strong> 1 mL (equivalent to 75 ug of D-Cloprostenol), in all its indications.\nInduction of labor: Administer after day 112 of gestation. In 70% of cases, delivery should occur 19 to 30 hours after treatment.<\/li>\n \t<li><strong>Sheep:<\/strong> 1 mL (equivalent to 75 ug of D-Cloprostenol).\n- For synchronization of estrus with progestogens: <span style=\"font-size: 1rem;\">apply a single dose after removal of the intravaginal device.\n<\/span>- For estrus synchronization with prostaglandins only:<span style=\"font-size: 1rem;\">  Give two doses 7 to 9 days apart. Estrus occurs 2 to 4 days after the second dose.<\/span><\/li>\n<\/ul>","tabla":null},{"titulo":"Contraindications","tipo_de_contenido":"contenido","contenido":"<ul>\n \t<li>Do not use in pregnant females, except as indicated (abortion or childbirth).<\/li>\n \t<li>Do not administer to animals that are hypersensitive to cloprostenol.<\/li>\n<\/ul>","tabla":null},{"titulo":"Adverse Effects and Adverse Reactions","tipo_de_contenido":"contenido","contenido":"They have not been described.","tabla":null},{"titulo":"Interactions","tipo_de_contenido":"contenido","contenido":"<ul>\n \t<li>Do not use in animals treated with non-steroidal anti-inflammatory drugs, as it inhibits the synthesis of endogenous prostaglandins.<\/li>\n \t<li>The activity of other oxytocic agents may be increased following administration of cloprostenol.<\/li>\n<\/ul>","tabla":null},{"titulo":"Special precautions for the operator","tipo_de_contenido":"contenido","contenido":"<ul>\n \t<li>Avoid contact with pregnant women and people suffering from respiratory tract diseases (such as asthma).<\/li>\n \t<li>Do not handle by people who are hypersensitive to Cloprostenol.<\/li>\n \t<li>Avoid contact of the product with the skin; In case of contamination, wash with plenty of water.<\/li>\n \t<li>In case of accidental injection, go immediately to a medical center and show the product label.<\/li>\n \t<li>Do not smoke, eat or drink during administration of the product.<\/li>\n<\/ul>","tabla":null},{"titulo":"Special warnings and precautions for use","tipo_de_contenido":"contenido","contenido":"Keep out of reach of children","tabla":null},{"titulo":"Safekeeping Period","tipo_de_contenido":"contenido","contenido":"<strong>Meat:<\/strong> 1 day\n<strong>Milk:<\/strong> 0 days","tabla":null},{"titulo":"Remarks","tipo_de_contenido":"contenido","contenido":"<strong>VETERINARY USE<\/strong>","tabla":null},{"titulo":"Special precautions for the disposal of unused product or waste material","tipo_de_contenido":"contenido","contenido":"Empty containers can be discarded as household waste, without any special precautions. Do not dispose of containers with product residues on the ground or in waterways. For expired or unused products, contact the manufacturing laboratory.","tabla":null},{"titulo":"Storage conditions","tipo_de_contenido":"contenido","contenido":"Store between 15 and 30\u00b0C, away from light. Once opened, use within 12 weeks. Discard the unused product after that period of time.","tabla":null},{"titulo":"Condition of Sale","tipo_de_contenido":"contenido","contenido":"Sale under prescription Withheld Veterinary Doctor.","tabla":null},{"titulo":"Records","tipo_de_contenido":"contenido","contenido":"Reg. SAG No 1600","tabla":null},{"titulo":"Presentation","tipo_de_contenido":"contenido","contenido":"Bottle with 20 mL and 50 mL","tabla":null},{"titulo":"Produced and distributed by","tipo_de_contenido":"contenido","contenido":"<strong><a title=\"Laboratorio Drag Pharma Chile Invetec S.A\" href=\"https:\/\/dragpharma.cl\/admin\/tabledit\/dragpharma.cl\" target=\"_blank\" rel=\"noopener\">Laboratorio Drag Pharma Chile Invetec S.A<\/a>.\n<\/strong>Lautaro N\u00b0 300. Quilicura. Santiago. Chile.","tabla":null}],"is_featured_product":"","related_prod":[9674,8687,9097]},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ovolute\u00ae - Drag Pharma<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dragpharma.cl\/en\/producto\/ovolute\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ovolute\u00ae - Drag Pharma\" \/>\n<meta property=\"og:description\" content=\"Ovolute\u00ae is a synthetic prostaglandin used for:   Induction or synchronization of estrus.  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