ROSTRUM® 5% - Injectable Solution


Broad spectrum antibacterial

Rostrum® 5%, is a broad spectrum antibacterial, indicated for the treatment of bacterial infections caused by microorganisms sensitive to Enrofloxacin.
In cattle and pigs, its use is indicated in the treatment of respiratory infections, digestive system infections, Agalactia Mastitis Metritis Syndrome in sows, and septic conditions caused by the following bacterial species: E. coli, Salmonella spp., Klebsiella spp. , Proteus, spp., Yersinia spp., Haemophilus spp., Pasteurella spp., Actinobacillus spp., Brucella spp., Campylobacter spp., Streptococcus spp, Staphylococcus spp., Bacteriodes spp., Bordetella spp. and Mycoplasma spp.

Technical Specification

Species


Bovines and pigs.

Dosage form


Injectable solution

Therapeutic action


Broad spectrum antibacterial

Composition


Each 100 mL contains:
Enrofloxacin ............................ 5 g
Excipients q.s. ................... 100 mL

Indications


Rostrum® 5%, is a broad spectrum antibacterial, indicated for the treatment of bacterial infections caused by microorganisms sensitive to Enrofloxacin.
In cattle and pigs, its use is indicated in the treatment of respiratory infections, digestive system infections, Agalactia Mastitis Metritis Syndrome in sows, and septic conditions caused by the following bacterial species: E. coli, Salmonella spp., Klebsiella spp. , Proteus, spp., Yersinia spp., Haemophilus spp., Pasteurella spp., Actinobacillus spp., Brucella spp., Campylobacter spp., Streptococcus spp, Staphylococcus spp., Bacteriodes spp., Bordetella spp. and Mycoplasma spp.

Route od administration and dosage


Route of administration:
Intramuscular (cattle and pigs) and subcutaneous (cattle).

Dose of the active principle:
In both species, 2.5 mg / Kg of weight, every 24 hours for 3 to 5 days. In acute infections, the dose can be increased to 5 mg / kg of weight, every 24 hours for 3 to 5 days.

Product dosage:
In both species, 1mL / 20 Kg of weight, every 24 hours for 3 to 5 days. In acute infections, the dose can be increased to 2 mL / 20 kg of weight, every 24 hours for 3 to 5 days.

Drug interactions


  • Enrofloxacin administered with theophylline can increase your serum levels.
  • Concomitant administration with other drugs that have hepatic metabolism may affect the pharmacokinetics of one or both drugs.

Contraindications


  • Do not administer Enrofloxacin to animals with hypersensitivity to Quinolones.
  • The use of Enrofloxacin can cause the formation of crystals in urine, for which it is recommended not to administer in dehydrated animals.
  • Do not use during pregnancy and lactation.
  • Do not use in breeding animals.

Special precautions for use


  • Avoid the use of Enrofloxacin in young growing animals due to the cartilaginous abnormalities that it can generate.
  • Fluoroquinolones, like Enrofloxacin, should not be used as the first line of treatment, unless there is no therapeutic alternative available. When used as a second treatment, it should be based on susceptibility studies.

Special precautions for the operator


  • Do not handle by people hypersensitive to quinolones.
  • In case of contact with skin, eyes or mucous membranes, wash immediately with plenty of water.
  • In case of accidental injection, go immediately to a medical center and show the product insert

Warnings


Keep out of the reach of children.

Adverse effects


  • Arthropathies have been reported in immature animals such as calves and piglets. The risk of arthropathy increases when the dose is increased.
  • Other adverse effects that have been reported in very rare cases (less than 1 animal in 10,000 animals, including isolated reports) include vomiting, anorexia, increased liver enzymes, ataxia, seizures, depression, lethargy and nervousness.

Observations


Special precautions for disposal of unused product or waste material:
Empty containers can be discarded as household waste, without any special precaution. Do not dispose of containers with product remains on the ground or watercourses. For expired or unused products, contact the manufacturing laboratory.

Conservation


Storage conditions:
Store between 15 and 30 °C, protected from light. Once the container is opened, use within 4 weeks. Discard unused product after that period of time.

Condition of sale


Sale under retained Veterinary Medical prescription.

Presentation


20 mL vial

Prepared by


Laboratorio Drag Pharma Chile Invetec S.A.

Records


Reg. SAG N° 723

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Drag Pharma Lab is not responsible for the consequences of misuse of the products, and the use of this information without consulting a veterinarian