ROSTRUM® 50 mg - Oral Tablet


Antibacterial

Rostrum®, is a broad spectrum antibacterial, recommended for the treatment of:

  • Gastrointestinal tract infections (Escherichia coli, Salmonella spp., Proteus spp.).
  • Respiratory tract infections (Pasteurella spp., Bordetella spp., Klebsiella spp.).
  • Genitourinary infections such as nephritis, pyelonephritis, cystitis. (Escherichia coli, Corynebacterium pyogenes, Staphylococcus aureus, Streptococcus spp. And Pseudomonas aeruginosa).
  • Skin infections
  • External auditory canal infections and otitis (Escherichia coli, Staphylococcus aureus, Streptococcus spp. And Pseudomonas aeruginosa).
  • Dermatitis, infected wounds (Escherichia coli, Klebsiella spp., Staphylococcus aureus, Streptococcus spp. And Pseudomonas aeruginosa).

Technical Specification

Species


Dogs and cats.

Dosage form


Oral Tablet

Therapeutic action


Antibacterial

Composition


Each tablet contains:
Enrofloxacin ....................... 50 mg
Excipients q.s.p .......... 1 tablet

Indications


Rostrum®, is a broad spectrum antibacterial, recommended for the treatment of:

  • Gastrointestinal tract infections (Escherichia coli, Salmonella spp., Proteus spp.).
  • Respiratory tract infections (Pasteurella spp., Bordetella spp., Klebsiella spp.).
  • Genitourinary infections such as nephritis, pyelonephritis, cystitis. (Escherichia coli, Corynebacterium pyogenes, Staphylococcus aureus, Streptococcus spp. And Pseudomonas aeruginosa).
  • Skin infections
  • External auditory canal infections and otitis (Escherichia coli, Staphylococcus aureus, Streptococcus spp. And Pseudomonas aeruginosa).
  • Dermatitis, infected wounds (Escherichia coli, Klebsiella spp., Staphylococcus aureus, Streptococcus spp. And Pseudomonas aeruginosa).

Use instructions


Administer directly into the oral cavity.

Route od administration and dosage


Oral administration.

Dosage: 1 tablet of 50 mg / 10 Kg of weight per day, for 7 to 10 days, equivalent to 5 mg / Kg of weight / day / for 7 to 10 days.

Half the dose can be administered twice a day.

Drug interactions


  • Compounds containing di or trivalent cations such as aluminum, calcium, magnesium, iron or zinc can decrease the absorption of Enrofloxacin. Thus, for example, antacids containing cations (Mg2 +, Al3 +, Ca2 +) can bind to Enrofloxacin and prevent its absorption.
  • Sucralfate can inhibit the absorption of Enrofloxacin. It is recommended to separate both dosages for at least two hours.
  • Enrofloxacin administered with theophylline can increase your serum levels. In dogs, theophylline clearance was reduced by 43% when co-administered with Enrofloxacin at a dose of 5 mg / kg every 24 hours.
  • Concomitant administration with other drugs that have hepatic metabolism may affect the pharmacokinetics of one or both drugs.

Contraindications


  • Enrofloxacin is contraindicated in animals with hypersensitivity to quinolones.
  • Do not administer to small to medium breed dogs, younger than 1 year, nor to large breed dogs younger than 1 ½ year.
  • Do not administer to cats younger than 8 weeks of age.
  • The use of Enrofloxacin can cause the formation of crystals in urine, therefore it is recommended not to administer in dehydrated animals.
  • It is not recommended for use in pregnancy and / or lactation.

Warnings


  • Keep out of the reach of children.
  • Fluoroquinolones, such as Enrofloxacin, should not be used as the first line of treatment, except that there is no therapeutic alternative available. When used as a second treatment, it should be based on susceptibility studies.

Adverse effects


  • Arthropathies have been reported in immature animals, especially dogs. The risk of arthropathy increases when the dose is increased, however, it has also been reported when the recommended doses are used in dogs.
  • Other side effects that have been described in very rare cases (less than 1 animal in 10,000 animals, including isolated reports) include vomiting, anorexia, increased liver enzymes, ataxia, seizures, depression, lethargy, and nervousness.

Observations


Special precautions for the disposal of unused product or waste material:
Discard the remains of unused product in its original container. Dispose of this product with caution with household waste.

Conservation


Store at room temperature below 30°C. Do not refrigerate or freeze.

Condition of sale


For Chile: Sales under prescription Veterinary Doctor withheld.
For Export: Sale under Veterinary Medical prescription.

Presentation


Case with 10 tablets.

Prepared by


Laboratorio Drag Pharma Chile Invetec S.A.

Records


Chile: Reg. SAG N° 602
Rep. Dominicana: Reg. Nº 8786
Bolivia: Reg. SENASAG PUV-F N° 007250/16
Costa Rica: Reg. N° MAG CL4-5-60-5759
Perú: Registro SENASA F.82.21.I.0385

Countries where it is marketed


Imported and distributed in Bolivia by:

ZOOFARMA

TEL: +(591)222-3357
Street Díaz Romero 1339, La Paz.

Imported and Distributed in Peru by:
Representaciones Durand SAC.
Av. Manuel Olguín N ° 501 Office N ° 604 Santiago de Surco Lima.

You have entered drug info or veterinary products intended exclusively (s) kind (s) indicated (s).

Drag Pharma Lab is not responsible for the consequences of misuse of the products, and the use of this information without consulting a veterinarian